Microbial Lipopeptides Stimulate Dendritic Cell Maturation Via Toll-Like Receptor 2
نویسندگان
چکیده
منابع مشابه
Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2.
The ability of dendritic cells (DC) to initiate immune responses in naive T cells is dependent upon a maturation process that allows the cells to develop their potent Ag-presenting capacity. Although immature DC can be derived in vitro by treatment of peripheral blood monocytes with GM-CSF and IL-4, additional signals such as those provided by TNF-alpha, CD40 ligand, or LPS are required for com...
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The ability of vaccination to empower natural immune defenses against viral infection is well illustrated by the worldwide eradication of smallpox and the partial elimination of polio after global vaccination efforts (74, 98). Unfortunately, these major successes have been infrequent, and diverse viruses continue to threaten our societies. The development of new vaccines, or the improvement of ...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2001
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.166.4.2444